Comparison of cholesterol levels among lipoprotein fractions separated by anion-exchange high-performance liquid chromatography in periparturient Holstein-Friesian dairy cows.

Content Provider	Europe PMC
Author	TAKAHASHI, Tomoya MORI, Akihiro ODA, Hitomi MURAYAMA, Isao KOUNO, Mitsuhiko SAKO, Toshinori
Copyright Year	2021
Abstract	Changes in lipoprotein profiles occur in dairy cows during the periparturient period andin cows with transition cow disease. Here, the lipoprotein profiles of Holstein–Friesiandairy cows during the periparturient period were obtained by anion-exchange,high-performance liquid chromatography to evaluate the usefulness of lipoprotein profileevaluation during the periparturient period and in cows with fatty liver and milk fever.Lipoprotein levels (including total and high- (HDL-C) and low-density lipoprotein (LDL-C)cholesterol) in 10 healthy cows were low 4 weeks prepartum, with the lowest values atcalving or within 1 week of calving; the values increased at 8 weeks postpartum. Thelipoprotein levels were measured in 16 cows diagnosed with fatty liver (n=10) or milkfever (n=6) and compared to 10 healthy dairy cows. A significant difference was observedin HDL-C between healthy cows (at calving and 1 week postpartum), and the fatty liver andmilk fever cows. Cows with fatty liver and milk fever had a lower mean HDL-C than the 10healthy dairy cows at calving and 1 week postpartum. HDL-C might be a good indicator ofenergy balance for differentiating healthy cows from those with transition cowdisease.
ISSN	09167250
Volume Number	83
PubMed Central reference number	PMC7972898
Issue Number	2
PubMed reference number	33281143
Journal	The Journal of Veterinary Medical Science [J. Vet. Med. Sci]
e-ISSN	13477439
DOI	10.1292/jvms.20-0361
Language	English
Publisher	The Japanese Society of Veterinary Science
Publisher Date	2020-12-07
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the CreativeCommons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0:https://creativecommons.org/licenses/by-nc-nd/4.0/) ©2021 The Japanese Society of Veterinary Science
Subject Keyword	dairy cow lipoprotein profile periparturient period transition cow disease
Content Type	Text
Resource Type	Article
Subject	Veterinary