Isolated interrupted aortic arch in an adult: A case report.

Content Provider	Europe PMC
Author	Dong, Shu-Wen Di, Duo-Duo Cheng, Guan-Xun
Copyright Year	2021
Abstract	BACKGROUNDInterrupted aortic arch (IAA) is a rare congenital heart disease defined by an interruption of the lumen and anatomical continuity between the ascending and descending major arteries. It is usually found within a few hours or days of birth. Without surgery, the chances of survival are low. If IAA patients have an effective collateral circulation established, they can survive into adulthood. However, IAA in adults is extremely rare, with few reported cases.CASE SUMMARYA 27-year-old woman presented with a 6-year history of progressively worsening shortness of breath and chest tightness on exertion. She had cyanotic lips and clubbing of the fingers. A transthoracic echocardiogram revealed an enlarged heart and dilation of the main pulmonary artery. There was an abnormal 9 mm passage between the descending aorta and pulmonary artery. The ventricular septal outflow tract had a 14 mm defect. Doppler ultrasound suggested a patent ductus arteriosus and computed tomographic angiography showed the absence of the aortic arch. The diagnoses were ventricular septal defect, patent ductus arteriosus, and definite interruption of the aortic arch. Although surgical correction was recommended, the patient declined due to the surgical risks and was treated with medications to reduce pulmonary artery pressure and treat heart failure. Her condition has been stable for 12 mo of follow-up.CONCLUSIONAlthough rare, IAA should be considered in adults with refractory hypertension or unexplained congestive heart failure.
Volume Number	9
PubMed Central reference number	PMC7852638
Issue Number	4
PubMed reference number	33585649
Journal	World Journal of Clinical Cases
e-ISSN	23078960
DOI	10.12998/wjcc.v9.i4.992
Language	English
Publisher	Baishideng Publishing Group Inc
Publisher Date	2021-02-01
Access Restriction	Open
Rights License	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Subject Keyword	Interrupted aortic arch Diagnostic imaging Multimodal imaging Patent ductus arteriosus Ventricular septal defect Case report
Content Type	Text
Resource Type	Article
Subject	Medicine