Bacillus licheniformis-Fermented Products Improve Growth Performance and Intestinal Gut Morphology in Broilers under Clostridium perfringens Challenge.

Content Provider	Europe PMC
Author	Cheng, Yeong-Hsiang Horng, Yi-Bing Dybus, Andrzej Yu, Yu-Hsiang
Copyright Year	2020
Abstract	Necrotic enteritis caused by Clostridium perfringens has reemerged as a severe poultry disease worldwide since the ban on the routine use of antibiotics in animal feed. Probiotics are considered alternatives to antibiotic growth promoters. Bacillus species are the most common microorganisms used as probiotics in the feed industry. The current study investigated the growth and surfactin levels of Bacillus licheniformis in solid-state fermentation using different substrates and evaluated the effects of B. licheniformis-fermented products on growth performance and intestinal morphology in broilers exposed to C. perfringens. The highest viable biomass and surfactin concentration of B. licheniformis-fermented products was observed at 2% molasses and 20% soybean meal supplementation during fermentation (P<0.05). B. licheniformis-fermented product-derived surfactin inhibited the growth of C. perfringens in vitro in a dose dependent manner (P<0.05). B. licheniformis-fermented product supplementation (2 g/kg) significantly improved the body weight and average daily gain weight of broilers challenged with C. perfringens (P<0.05). B. licheniformis-fermented products significantly alleviated necrotic lesions and ameliorated intestinal morphology in broilers exposed to C. perfringens (P<0.05). Collectively, these observations demonstrate that B. licheniformis-fermented products improve growth performance and gut morphology in broilers under C. perfringens challenge. B. licheniformis-fermented products may have the potential to be used as alternatives to antibiotic growth promoters for preventive treatments against C. perfringens in broilers.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7837812&blobtype=pdf
Page Count	10
ISSN	13467395
Journal	The Journal of Poultry Science [J Poult Sci]
Volume Number	58
DOI	10.2141/jpsa.0200010
PubMed Central reference number	PMC7837812
Issue Number	1
PubMed reference number	33519284
e-ISSN	13490486
Language	English
Publisher	Japan Poultry Science Association
Publisher Date	2021-01-01
Access Restriction	Open
Rights License	The Journal of Poultry Science is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-sa/4.0/). 2020, Japan Poultry Science Association.
Subject Keyword	Bacillus licheniformis broiler Clostridium perfringens fermented products intestinal morphology
Content Type	Text
Resource Type	Article
Subject	Animal Science and Zoology