NDLI: Huanglian Jiedu Decoction for treatment of multiple myeloma: A protocol for a systematic review and meta-analysis.

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Huanglian Jiedu Decoction for treatment of multiple myeloma: A protocol for a systematic review and meta-analysis.

Content Provider	Europe PMC
Author	An, Na Li, Yiwei Huang, Xilian Chen, Can Xie, Yaping
Copyright Year	2020
Abstract	AbstractBackground:Multiple myeloma can lead to lots of clinical problems including pain, fatigue, anemia, infections, renal failure, and so on. Huanglian Jiedu Decoction is a common conservative treatment for this disease in China. Therefore, we conducted a systematic review and meta-analysis to explore the efficacy of Huanglian Jiedu Decoction in the treatment of multiple myeloma.Methods:A systematic literature search for studies will be performed in 8 databases, including PubMed, Web of Science, Embase, the Cochrane library, ClinicalTrials.gov databases, Chinese National Knowledge Infrastructure Database, Wanfang database, and VIP database. The methodological quality of the included studies using the risk bias assessment tool of Cochrane. And the level of evidence for results is assessed by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method. Statistical analysis is conducted with Revman 5.3.Results:This systematic review and meta-analysis will provide a synthesis of existed evidences for Huanglian Jiedu Decoction on multiple myeloma.Conclusion:The conclusion of this study will provide evidence to assess effectiveness of Huanglian Jiedu Decoction on multiple myeloma, which can further guide clinical decision-making.INPLASY registration number:INPLASY202060094
ISSN	00257974
Journal	Medicine
Volume Number	99
PubMed Central reference number	PMC7748179
Issue Number	51
PubMed reference number	33371054
e-ISSN	15365964
DOI	10.1097/md.0000000000022378
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2020-12-01
Publisher Place	Hagerstown, MD
Access Restriction	Open
Rights License	This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc.
Subject Keyword	Huanglian Jiedu Decoction meta-analysis multiple myeloma protocol
Content Type	Text
Resource Type	Article
Subject	Medicine

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