Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response.

Content Provider	Europe PMC
Author	Querido, Sara Calça, Rita Weigert, André Francisco, Diogo Adragão, Teresa Ana Pessanha, Maria Gomes, Perpétua Rodrigues, Luís Figueira, João M. Cardoso, Conceição Machado, Domingos
Abstract	AbstractKidney transplant (KT) recipients are at an increased risk for severe COVID‐19 because of their immunosuppressed state. A 42‐year‐old KT patient was diagnosed with COVID‐19 three months after KT. Despite lymphopenia and several risk factors, he had a mild disease course. Nasopharyngeal real‐time reverse transcriptase polymerase chain reaction for SARS‐CoV‐2 became negative 48 days after detection. SARS‑CoV‑2 IgG antibodies became negative after day 40. TTV DNA load increased with the onset COVID‐19 and reduced after its resolution. This is the first report where TTV DNA load was measured during the course of COVID‐19.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7744855&blobtype=pdf
ISSN	13982273
Journal	Transplant Infectious Disease [Transpl Infect Dis]
Volume Number	23
DOI	10.1111/tid.13524
PubMed Central reference number	PMC7744855
Issue Number	2
PubMed reference number	33226684
e-ISSN	13993062
Language	English
Publisher	John Wiley and Sons Inc.
Publisher Date	2020-12-06
Publisher Place	Hoboken
Access Restriction	Open
Rights License	This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. © 2020 Wiley Periodicals LLC
Subject Keyword	COVID‐19 kidney transplant SARS‐CoV‐2 torquetenovirus
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Transplantation