Comparative Findings Between ⁶⁸Ga-PSMA and ¹⁸F-FDG PET/CT for Hepatocellular Carcinoma

Content Provider	Europe PMC
Author	Erhamamcı, Seval Aslan, Nesrin
Copyright Year	2020
Abstract	We have reported here the case of a 69-year-old man who presented with spinal cord compression due to bone metastases as the first manifestation of hepatocellular carcinoma (HCC). For the initial staging, the patient underwent 18F-fluorodeoxyglucose (FDG) positron emission tomography/computerized tomography (PET/CT) imaging, which demonstrated mild 18F-FDG uptake in the multiple expansile osteolytic bone lesions, but no remarkable atypical 18F-FDG uptake in the liver lesion on low-doses CT. An additional PET/CT scan was performed to evaluate the prostate-specific membrane antigen (PSMA) expression, which has recently been reported to be a potential biological marker in a variety of tumors including HCC. High PSMA uptake was recorded in both the metastatic bone lesions and the primary liver lesion/tumor by the 68Ga-PSMA PET/CT.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7583742&blobtype=pdf
ISSN	21461414
Journal	Molecular Imaging and Radionuclide Therapy [Mol Imaging Radionucl Ther]
Volume Number	29
DOI	10.4274/mirt.galenos.2020.50455
PubMed Central reference number	PMC7583742
Issue Number	3
PubMed reference number	33094578
e-ISSN	21471959
Language	English
Publisher	Galenos Publishing
Publisher Date	2020-10-01
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ©Copyright 2020 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.
Subject Keyword	Hepatocellular carcinoma bone metastases PET/CT 68Ga-PSMA 18F-FDG
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging