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A Review on Semaglutide: An Oral Glucagon-Like Peptide 1 Receptor Agonist in Management of Type 2 Diabetes Mellitus.
| Content Provider | Europe PMC |
|---|---|
| Author | Kalra, Sanjay Sahay, Rakesh |
| Abstract | Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are a well-established class of glucose-lowering drugs. GLP-1 RAs can be classified according to their structure, duration of action and mode of administration. This review describes the basic and clinical pharmacology of orally administered semaglutide. It highlights the PIONEER clinical trial programme results, and reviews the efficacy, safety and tolerability. |
| ISSN | 18696953 |
| Journal | Diabetes Therapy |
| Volume Number | 11 |
| PubMed Central reference number | PMC7434819 |
| Issue Number | 9 |
| PubMed reference number | 32725484 |
| e-ISSN | 18696961 |
| DOI | 10.1007/s13300-020-00894-y |
| Language | English |
| Publisher | Springer Healthcare |
| Publisher Date | 2020-07-28 |
| Publisher Place | Cheshire |
| Access Restriction | Open |
| Rights License | Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/. © The Author(s) 2020 |
| Subject Keyword | GLP-1 receptor agonists GLP-1 RA Glucagon-like peptide Orally administered semaglutide Pioneer trial |
| Content Type | Text |
| Resource Type | Article |
| Subject | Endocrinology, Diabetes and Metabolism Internal Medicine |