Cerebrospinal nematodosis caused by Parelaphostrongylus species in an adult bull.

Content Provider	Europe PMC
Author	MacKay, Evelyn E. Fratzke, Alycia P. Gerhold, Richard W. Porter, Brian F. Washburn, Kevin E.
Copyright Year	2020
Abstract	A 2-y-old Brahman bull was presented with progressive hindlimb ataxia and paraparesis that led to recumbency. Postmortem examination revealed scattered pinpoint, red-brown foci within the brainstem and gray matter of the spinal cord, and a larger lesion within the spinal cord at the level of T13. Histology of the section of T13 contained cross-sections of nematodes consistent with Parelaphostrongylus tenuis. Evidence of inflammation was present in other affected areas of the spinal cord and brain. DNA extraction and nested PCR were performed, which demonstrated 98% identity and 100% coverage to both P. tenuis and P. andersoni. Our case highlights the utility of DNA sequencing in parasite identification.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7377620&blobtype=pdf
ISSN	10406387
Volume Number	32
DOI	10.1177/1040638720915530
PubMed Central reference number	PMC7377620
Issue Number	3
PubMed reference number	32242771
Journal	Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest]
e-ISSN	19434936
Language	English
Publisher	SAGE Publications
Publisher Date	2020-04-03
Publisher Place	Sage CA: Los Angeles, CA
Access Restriction	Open
Rights License	© The Author(s) 2020
Subject Keyword	cattle DNA sequencing meningeal worm nematodosis Parelaphostrongylus tenuis PCR
Content Type	Text
Resource Type	Article
Subject	Veterinary