The role of Visual Evoked Potential (VEP) in monitoring the progression and in guiding the treatment of glaucoma patients with poor compliance.

Content Provider	Europe PMC
Author	Firan, Anne Marie Iancu, Raluca Claudia Bujor, Inna Adriana Ciuluvică, Radu Constantin Tudosescu, Ruxandra Ungureanu, Emil Pașca, Irena Gabriela Voinea, Liliana Istrate, Sînziana
Copyright Year	2020
Abstract	Objectives: The objectives of the present study were to analyze the possibility of using pattern VEPs (VEP of pattern type) in glaucoma patients and their role in the follow-up and coordination/ management of anti-glaucoma treatment.Patients and Methods: This is a prospective study on 54 eyes of 30 consecutive glaucoma patients, whose compliance capacity did not allow automatic perimetry and OCT scan to be carried out.The patients were divided into two groups: group A – the study group and group B – the control group.All patients underwent FO exam and pachymetry, plus VEP exam for group A patients.Patients were analyzed at the initial visit and at 1 month, 3, 6, 12 months.Statistical analysis was made using t-test, ANOVA, Fisher test and Pearson correlation coefficient.Results: These participants presented a positive correlation between C/ D ratio and the latency of the P100 wave at 1 degree and a negative correlation between C/ D ratio and the amplitude of the P100 wave both at 1 degree (60 arc minutes) and at 0.25 degrees (15 arc minutes). During the study, the values of the latent P100 changed statistically at 6 months and at 1 year.Using all the data, the authors of the study considered it necessary to modify the treatment for 2 patients out of 13 in group B and for 9 patients out of 16 in group A (p = 0,02892).Conclusions: VEP supplies additional/ further data that significantly help guiding the treatment and monitoring the progression, therefore, it should be part of the routine examination for these patients.Further studies are necessary to deepen our understanding of the visual evoked potentials utility.
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ISSN	24574325
Journal	Romanian Journal of Ophthalmology [Rom J Ophthalmol]
Volume Number	64
PubMed Central reference number	PMC7339685
Issue Number	2
PubMed reference number	32685788
e-ISSN	25012533
Language	English
Publisher	Romanian Society of Ophthalmology
Publisher Date	2020-04-01
Publisher Place	Romania
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original work is properly cited. ©Romanian Society of Ophthalmology
Subject Keyword	visual evoked potential glaucoma amplitude latency
Content Type	Text
Resource Type	Article
Subject	Medicine