Photocatalytic Deoxygenation of Sulfoxides Using Visible Light: Mechanistic Investigations and Synthetic Applications.

Content Provider	Europe PMC
Author	Clarke, AimeeK. Parkin, Alison Taylor, Richard J. K. Unsworth, William P. Rossi-Ashton, James A.
Copyright Year	2020
Abstract	Thephotocatalytic deoxygenation of sulfoxides to generate sulfidesfacilitated by either Ir[(dF(CF3)ppy)2(dtbbpy)]PF6 or fac-Ir(ppy)3 is reported.Mechanistic studies indicate that a radical chain mechanism operates,which proceeds via a phosphoranyl radical generated from a radical/polarcrossover process. Initiation of the radical chain was found to proceedvia two opposing photocatalytic quenching mechanisms, offering complementaryreactivity. The mild nature of the radical deoxygenation process enablesthe reduction of a wide range of functionalized sulfoxides, includingthose containing acid-sensitive groups, in typically high isolatedyields.
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Journal	ACS Catalysis [ACS Catal]
Volume Number	10
DOI	10.1021/acscatal.0c00690
PubMed Central reference number	PMC7304878
Issue Number	10
PubMed reference number	32582464
e-ISSN	21555435
Language	English
Publisher	American Chemical Society
Publisher Date	2020-04-17
Access Restriction	Open
Rights License	This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited. Copyright © 2020 American Chemical Society
Subject Keyword	sulfoxide deoxygenation reduction radical visible light photoredox catalysis sulfide radical cation
Content Type	Text
Resource Type	Article
Subject	Chemistry Catalysis