Loading...
Please wait, while we are loading the content...
Similar Documents
Multiple versus single doses of dexamethasone in total hip arthroplasty: A protocol of randomized controlled trial.
| Content Provider | Europe PMC |
|---|---|
| Author | Zhang, Bangjian Sun, Shaoqiong Sheng, Bo |
| Copyright Year | 2020 |
| Abstract | AbstractBackground:Reduction of post-operative pain, nausea, and vomiting in patients undergoing total hip arthroplasty (THA) may facilitate earlier discharge from hospital and reduce healthcare costs. The recommended dose regimen of dexamethasone in THA has not been determined. The purpose of this study was performed to compare the efficiency of multiple versus single doses of dexamethasone for early postoperative pain treatment after THA.Methods:This study was a randomized controlled trial which conducted in our hospital. Informed consent for participation in this trial was obtained from each patient before surgery. Two hundred patients undergoing THA received 1 dose of intravenous dexamethasone and 1 dose of normal saline (Group A), or 2 doses of intravenous dexamethasone (Group B). The primary outcome was visual analog scale pain scores in the immediate postoperative period. Secondary outcomes included postoperative opioid use, length of hospital stay, activity level during physical therapy, and hip range of motion.Results:This clinical trial might provide some insights to estimate the safety of dexamethasone.Trial registration:This study protocol was registered in Research Registry (researchregistry5460). |
| ISSN | 00257974 |
| Journal | Medicine |
| Volume Number | 99 |
| PubMed Central reference number | PMC7220463 |
| Issue Number | 19 |
| PubMed reference number | 32384500 |
| e-ISSN | 15365964 |
| DOI | 10.1097/md.0000000000020147 |
| Language | English |
| Publisher | Wolters Kluwer Health |
| Publisher Date | 2020-05-01 |
| Access Restriction | Open |
| Rights License | This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. |
| Subject Keyword | dexamethasone pain control randomized controlled trial study protocol total hip arthroplasty |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
