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Thromboprophylaxis after bariatric surgery.
| Content Provider | Europe PMC |
|---|---|
| Author | Almarshad, Feras M. Almegren, Mosaad Alshuaibi, Turki Alobaodi, Nadiah Almutawa, Ali Basunbl, Hajer AlGahtani, Farjah Al Rawahi, Bader |
| Copyright Year | 2020 |
| Abstract | Background Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is a known cause of morbidity and mortality after bariatric surgery. However, the data concerning appropriate thromboprophylaxis after bariatric surgery is uncertain. The objective of this study was to evaluate the efficacy and safety of extended duration thromboprophylaxis in post-bariatric surgery patients. Methods We conducted a retrospective study of consecutive patients who underwent bariatric surgery from November 2014 to October 2018 at King Fahad General Hospital in Jeddah, Saudi Arabia. All included patients were treated with extended duration thromboprophylaxis. Results We identified 374 patients who underwent bariatric surgery during the study period. Of these, 312 patients (83%) were followed for at least 3 months. The most common type of surgery was a laparoscopic sleeve gastrectomy (N=357) and the median weight was 110 kg. The cumulative incidence of symptomatic postoperative VTE at 3 months was 0.64% (95% confidence interval, 0.20–1.52). All events occurred after hospital discharge. The most commonly used pharmacological prophylaxis (91%) for VTE prevention after bariatric surgery was enoxaparin 40 mg subcutaneously twice daily for 10–14 days after hospital discharge. There were no reported cases of bleeding or VTE related mortality after 3 months. Conclusion Extended thromboprophylaxis after bariatric surgery appears to be an effective and safe strategy for VTE prevention. Large prospective studies are needed to evaluate the optimal thromboprophylaxis regimen after bariatric surgery. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7106117&blobtype=pdf |
| ISSN | 2287979X |
| Volume Number | 55 |
| DOI | 10.5045/br.2020.55.1.44 |
| PubMed Central reference number | PMC7106117 |
| Issue Number | 1 |
| PubMed reference number | 32269974 |
| Journal | Blood research [Blood Res] |
| e-ISSN | 22880011 |
| Language | English |
| Publisher | Korean Society of Hematology |
| Publisher Date | 2020-03-30 |
| Access Restriction | Open |
| Rights License | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. © 2020 Korean Society of Hematology |
| Subject Keyword | Bariatric surgery Venous thromboembolism Deep vein thrombosis Pulmonary embolism Thromboprophylaxis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology |
