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Sleep Apnea and Sudden Cardiac Death.
| Content Provider | Europe PMC |
|---|---|
| Author | Blackwell, Jacob N. Walker, McCall Stafford, Patrick Estrada, Sebastian Adabag, Selcuk Kwon, Younghoon |
| Copyright Year | 2019 |
| Abstract | Sleep plays an integral role in maintaining health and quality of life. Obstructive sleep apnea (OSA) is a prevalent sleep disorder recognized as a risk factor for cardiovascular disease and arrhythmia. Sudden cardiac death (SCD) is a common and devastating event. Out-of-hospital SCD accounts for the majority of deaths from cardiac disease, which is the leading cause of death globally. A limited but emerging body of research has further elaborated on the link between OSA and SCD. In this article, we aim to provide a critical review of the existing evidence by addressing the following questions: (1) what epidemiologic evidence exists linking OSA to SCD; (2) what evidence exists for a pathophysiologic connection between OSA and SCD; (3) are there electrocardiographic markers of SCD found in patients with OSA; (4) does heart failure represent a major effect modifier regarding the relationship between OSA and SCD; and (5) what is the impact of sleep apnea treatment on SCD and cardiovascular outcomes. Finally, we elaborate on ongoing research to enhance our understanding of the OSA-SCD association. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7083593&blobtype=pdf |
| Journal | Circulation Reports [Circ Rep] |
| Volume Number | 1 |
| PubMed Central reference number | PMC7083593 |
| Issue Number | 12 |
| PubMed reference number | 32201748 |
| e-ISSN | 24340790 |
| DOI | 10.1253/circrep.cr-19-0085 |
| Language | English |
| Publisher | The Japanese Circulation Society |
| Publisher Date | 2019-12-10 |
| Access Restriction | Open |
| Rights License | This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license. Copyright © 2019, THE JAPANESE CIRCULATION SOCIETY |
| Subject Keyword | Obstructive sleep apnea QTc Sleep Sudden cardiac death Ventricular arrhythmia |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
