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PET/CT and PET/MRI in ophthalmic oncology (Review).
| Content Provider | Europe PMC |
|---|---|
| Author | Kalemaki, Maria S. Karantanas, Apostolos H. Exarchos, Dimitris Detorakis, Efstathios T. Zoras, Odysseas Marias, Kostas Millo, Corina Bagci, Ulas Pallikaris, Ioannis Stratis, Andreas Karatzanis, Ioannis Perisinakis, Kostas Koutentakis, Pavlos Kontadakis, Georgios A. Spandidos, Demetrios A. Tsatsakis, Aristidis Papadakis, Georgios Z. |
| Copyright Year | 2020 |
| Abstract | Orbital and ocular anatomy is quite complex, consisting of several tissues, which can give rise to both benign and malignant tumors, while several primary neoplasms can metastasize to the orbital and ocular space. Early detection, accurate staging and re-staging, efficient monitoring of treatment response, non-invasive differentiation between benign and malignant lesions, and accurate planning of external radiation treatment, are of utmost importance for the optimal and individualized management of ophthalmic oncology patients. Addressing these challenges requires the employment of several diagnostic imaging techniques, such as high-definition digital fundus photography, ultrasound imaging, optical coherence tomography, optical coherence tomography (OCT)-angiography, computed tomography (CT) and magnetic resonance imaging (MRI). In recent years, technological advances have enabled the development of hybrid positron emission tomography (PET)/CT and PET/MRI systems, setting new standards in cancer diagnosis and treatment. The capability of simultaneously targeting several cancer-related biochemical procedures using positron emitting-radiopharmaceuticals, while morphologically characterizing lesions by CT or MRI, together with the intrinsic quantitative capabilities of PET-imaging, provide incremental diagnostic information, enabling accurate, highly efficient and personalized treatment strategies. Aim of the current review is to discuss the current applications of hybrid PET/CT and PET/MRI imaging in the management of patients presenting with the most commonly encountered orbital and ocular tumors. |
| ISSN | 10196439 |
| Journal | International Journal of Oncology |
| Volume Number | 56 |
| PubMed Central reference number | PMC6959466 |
| Issue Number | 2 |
| PubMed reference number | 31939615 |
| e-ISSN | 17912423 |
| DOI | 10.3892/ijo.2020.4955 |
| Language | English |
| Publisher | D.A. Spandidos |
| Publisher Date | 2020-01-03 |
| Access Restriction | Open |
| Rights License | This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. Copyright: © Kalemaki et al. |
| Subject Keyword | orbital tumors ocular tumors positron emission tomography/computed tomography positron emission tomography/magnetic resonance imaging cancer staging |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
