Correlates of Human Papillomavirus Vaccination and Association with HPV-16 and HPV-18 DNA Detection in Young Women.

Content Provider	Europe PMC
Author	Feder, Molly A. Kulasingam, Shalini L. Kiviat, Nancy B. Mao, Constance Nelson, Erik J. Winer, Rachel L. Whitham, Hilary K. Lin, John Hawes, Stephen E.
Copyright Year	2019
Abstract	Abstract Background: Despite a reduction in the prevalence of vaccine-preventable types of human papillomavirus (HPV), attributed to increased HPV vaccine uptake, HPV continues to be a major cause of cancer in the United States. Methods: We assessed factors associated with self-reported HPV vaccine uptake, HPV vaccination effectiveness, using DNA testing to assess HPV types 16 and/or 18 (HPV 16/18) positivity, and patterns of HPV vaccination in 375 women aged 21–29 years who were eligible to receive catch-up vaccination, using baseline data collected from March 2012 to December 2014 from a randomized controlled trial evaluating a novel approach to cervical cancer screening. Results: More than half (n = 228, 60.8%) of participants reported receipt of at least one HPV vaccine dose and 16 (4.3%) tested positive for HPV 16/18 at baseline. College-educated participants were four times more likely to have been vaccinated than those reporting high school education or less. 56.5% of HPV-vaccinated participants reported first dose after age 18 and 68.4% after first vaginal intercourse. Women vaccinated after age 18 and women vaccinated after first vaginal intercourse were somewhat more likely to be infected with HPV 16/18 infection compared with women vaccinated earlier, but these associations did not reach statistical significance. Conclusions: HPV vaccination is common among college-educated women in the catch-up population but less common among those without college education. Contrary to current guidelines, catch-up females frequently obtain HPV vaccination after age 18 and first vaginal intercourse. Women without a college education represent an ideal population for targeted HPV vaccination efforts that emphasize vaccination before sexual debut.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6797070&blobtype=pdf
Page Count	8
ISSN	15409996
Volume Number	28
DOI	10.1089/jwh.2018.7340
PubMed Central reference number	PMC6797070
Issue Number	10
PubMed reference number	31264912
Journal	Journal of Women's Health [J Womens Health (Larchmt)]
e-ISSN	1931843X
Language	English
Publisher	Mary Ann Liebert, Inc., publishers
Publisher Date	2019-07-02
Publisher Place	USA
Access Restriction	Open
Rights License	Copyright 2019, Mary Ann Liebert, Inc., publishers
Subject Keyword	HPV vaccination human papillomavirus correlates catch-up population
Content Type	Text
Resource Type	Article
Subject	Medicine