Fecal Microbiota Transplantation for the Management of Clostridium difficile Infection.

Content Provider	Europe PMC
Author	Paknikar, Raghavendra Pekow, Joel
Copyright Year	2018
Abstract	Abstract The clinical burden of Clostridium difficile infection (CDI) continues to grow. Despite the multitude of treatment options that have been developed and tested to combat the morbidity and death associated with CDI, recurrence remains common. As such, treatment modalities such as fecal microbiota transplantation (FMT) have become studied increasingly; FMT serves to transplant stool from carefully selected healthy subjects into C. difficile positive patients through a variety of delivery routes. In doing so, FMT is hypothesized to correct dysbiosis of the recipient gut microbiome addressing the root cause of the pathogenesis of C. difficile infection. A growing body of evidence shows FMT to be efficacious in this setting, and the study of FMT accordingly continues to evolve to identify novel indications for its utilization.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6302669&blobtype=pdf
Page Count	7
ISSN	10962964
Volume Number	19
DOI	10.1089/sur.2018.221
PubMed Central reference number	PMC6302669
Issue Number	8
PubMed reference number	30300561
Journal	Surgical Infections [Surg Infect (Larchmt)]
e-ISSN	15578674
Language	English
Publisher	Mary Ann Liebert, Inc., publishers
Publisher Date	2018-10-09
Publisher Place	USA
Access Restriction	Open
Rights License	Copyright 2018, Mary Ann Liebert, Inc., publishers
Subject Keyword	Clostridium difficile Clostridium difficile colitis fecal microbiota transplantation
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Surgery Microbiology (medical)