Does water stress promote the proteome-wide adjustment of intrinsically disordered proteins in plants?

Content Provider	Europe PMC
Author	Zamora-Briseño, Jesús Alejandro Reyes-Hernández, Sandi Julissa Zapata, Luis Carlos Rodríguez
Abstract	Plant response to water stress involves the activation of mechanisms expected to help them cope with water scarcity. Among these mechanisms, proteome-wide adjustment is well known. This includes actions to save energy, protect cellular and molecular components, and maintain vital functions of the cell. Intrinsically disordered proteins, which are proteins without a rigid three-dimensional structure, are seen as emerging multifunctional cellular components of proteomes. They are highly abundant in eukaryotic proteomes, and numerous functions for these proteins have been proposed. Here, we discuss several reasons why the collection of intrinsically disordered proteins in a proteome (disordome) could be subjected to an active regulation during conditions of water scarcity in plants. We also discuss the potential misinterpretations of disordome content estimations made so far due to bias-prone data and the need for reliable analysis based on experimental data in order to acknowledge the plasticity nature of the disordome.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6111090&blobtype=pdf
ISSN	13558145
Volume Number	23
DOI	10.1007/s12192-018-0918-x
PubMed Central reference number	PMC6111090
Issue Number	5
PubMed reference number	29860709
Journal	Cell Stress & Chaperones
e-ISSN	14661268
Language	English
Publisher	Springer Netherlands
Publisher Date	2018-06-02
Publisher Place	Dordrecht
Access Restriction	Open
Rights License	© Cell Stress Society International 2018
Subject Keyword	Water stress Disordome Intrinsically disordered proteins/regions
Content Type	Text
Resource Type	Article
Subject	Cell Biology Biochemistry