Cardiopulmonary Bypass in the Setting of Waldenström's Macroglobulinemia.

Content Provider	Europe PMC
Author	D’Aloiso, Brandon D. Rupchak, Sarah S. Gettle, Kaitlin J. Lima, Claudio Rush, Robert D.
Copyright Year	2018
Abstract	: Waldenström’s Macroglobulinemia (WM) is a rare lymphoma caused by the overproduction of immunoglobulin M (IgM). The elevated level of IgM causes serum hyperviscosity, cold agglutinins, and cryoglobulinemia. Anemia is also present because of impaired production of erythrocytes. For these reasons, placing a patient with WM on cardiopulmonary bypass (CPB) requires careful preparation. In this case, the patient was a 73-year-old male with known Waldenström’s disease who required coronary artery bypass graft surgery. This report details the perioperative considerations used for successful CPB on a Waldenström’s patient. Critical to this case was the use of plasmapheresis before surgery. Temperature management and acid/base status were carefully controlled. A successful coronary revascularization surgery was performed. Many of the Wadenstrom’s disease complications expected on CPB failed to materialize.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6002643&blobtype=pdf
Page Count	4
ISSN	00221058
Volume Number	50
PubMed Central reference number	PMC6002643
Issue Number	2
PubMed reference number	29921992
Journal	The Journal of Extra-corporeal Technology [J Extra Corpor Technol]
Language	English
Publisher	American Society of ExtraCorporeal Technology
Publisher Date	2018-06-01
Access Restriction	Open
Rights License	© Copyright 2018 AMSECT
Subject Keyword	Waldenström’s Macroglobulinemia hyperviscosity cardiopulmonary bypass cold agglutinins
Content Type	Text
Resource Type	Article
Subject	Health Professions Medicine Cardiology and Cardiovascular Medicine