NDLI: Molecular epidemiological survey of canine parvovirus in domestic dogs in four provinces, China.

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Molecular epidemiological survey of canine parvovirus in domestic dogs in four provinces, China.

Content Provider	Europe PMC
Author	Wu, Hongchao Li, Xiangdong Wang, Lingxiao Liu, Yuxiu Tian, Kegong
Abstract	Canine parvovirus (CPV) can cause severe disease in animals, especially in dogs, and continuously generates new variants. In this study, the complete VP2 genes of 59 CPV isolates from clinical diseased dogs between 2015 and 2016 in 4 Chinese provinces were sequenced and analyzed. The results showed that new CPV-2a was still the prominent CPV genotype, followed by CPV-2c and new CPV-2b. CPV-2c with Ala5Gly and Gln370Arg mutations was first detected in Henan, Guangxi and Jiangsu provinces in China. A phylogenetic tree based on VP2 sequences showed that all isolates in this study formed a close lineage which separated from foreign isolates. The above results indicated that point mutations in VP2 were constantly occurring along with the widespread of CPV in China. Electronic supplementary material The online version of this article (10.1007/s13337-018-0427-7) contains supplementary material, which is available to authorized users.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5877851&blobtype=pdf
ISSN	23473584
Volume Number	29
DOI	10.1007/s13337-018-0427-7
PubMed Central reference number	PMC5877851
Issue Number	1
PubMed reference number	29607369
Journal	VirusDisease
e-ISSN	23473517
Language	English
Publisher	Springer India
Publisher Date	2018-02-16
Publisher Place	New Delhi
Access Restriction	Open
Rights License	© Indian Virological Society 2018
Subject Keyword	Canine parvovirus Epidemiological survey VP2 gene Point mutation
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Virology

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