NDLI: Bilateral Hypopyon Uveitis in Chronic Myeloid Leukemia.

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Bilateral Hypopyon Uveitis in Chronic Myeloid Leukemia.

Content Provider	Europe PMC
Author	Tyagi, Mudit Govindhari, Vishal Pappuru, Rajeev R. Ambiya, Vikas
Copyright Year	2017
Abstract	Background A leukemic hypopyon is considered an early sign of central nervous system involvement or systemic relapse. A differential diagnosis of masquerade syndromes should be considered in cases of hypopyon uveitis that are atypical or unresponsive to treatment. We report a case of a 45-year-old man who presented with bilateral hypopyon uveitis and was subsequently diagnosed as having chronic myeloid leukemia. Method Retrospective case review. Results A 45-year-old diabetic male presented with diminished vision in both eyes for 10 days. Ophthalmic evaluation revealed rubeosis iridis, hypopyon, and signs of proliferative diabetic retinopathy with panretinal laser photocoagulation scars. He subsequently presented 1 week later with a bloodstained hypopyon in his right eye and a persistent hypopyon in his left eye. A peripheral blood smear and subsequent bone marrow trephine biopsy confirmed the diagnosis of chronic myeloid leukemia in blast crisis and he was referred to an oncologist for further management. Conclusion A recalcitrant or atypical hypopyon uveitis can be an indicator of a blast crisis or a central nervous system involvement or sign of a relapse in cases of leukemia. The presence of unusual bloodstained hypopyon helped in identifying the presence of chronic myeloid leukemia and aided in a prompt oncology consultation.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5757618&blobtype=pdf
Page Count	4
ISSN	22964681
Volume Number	4
DOI	10.1159/000475718
PubMed Central reference number	PMC5757618
Issue Number	1
PubMed reference number	29344492
Journal	Ocular Oncology and Pathology [Ocul Oncol Pathol]
e-ISSN	22964657
Language	English
Publisher	Karger Publishers
Publisher Date	2017-06-03
Publisher Place	Allschwilerstrasse 10, CH-4055 Basel, Switzerland
Access Restriction	Open
Rights License	Copyright © 2017 by S. Karger AG, Basel
Subject Keyword	Hypopyon Chronic myeloid leukemia Masquerade syndromes
Content Type	Text
Resource Type	Article
Subject	Nursing

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