NDLI: Treatment of Cerebral Palsy with Stem Cells: A Report of 17 Cases.

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Treatment of Cerebral Palsy with Stem Cells: A Report of 17 Cases.

Content Provider	Europe PMC
Author	Abi Chahine, Nassim H. Wehbe, Tarek W. Hilal, Ramzi A. Zoghbi, Victoria V. Melki, Alia E. Bou Habib, Emil B.
Copyright Year	2016
Abstract	Cerebral Palsy (CP) is a disabling condition that affects a child’s life and his/her family irreversibly. It is usually a non-progressive condition but improvement over time is rarely seen. The condition can be due to prenatal hypoxia, metabolic, genetic, infectious, traumatic or other causes. It is therefore a heterogeneous group that results in functional motor disability associated with different degrees of cognitive abnormalities. There are no treatments that can cure or even improve CP and the best available approach aims at functional, social and nutritional supportive care and counseling. In this paper, we report 17 sequential patients with CP treated with intrathecal administration of Bone Marrow Mononuclear Cells (BMMC). All patients had an uneventful post-injection course with 73% of the evaluable patients treated having a good response using the Gross Motor Function Classification System (GMFCS). The average improvement was 1.3 levels on the GMFCS with cognitive improvements as well.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4961108&blobtype=pdf
ISSN	20053606
Journal	International Journal of Stem Cells [Int J Stem Cells]
Volume Number	9
DOI	10.15283/ijsc.2016.9.1.90
PubMed Central reference number	PMC4961108
Issue Number	1
PubMed reference number	27426090
e-ISSN	20055447
Language	English
Publisher	Korean Society for Stem Cell Research
Publisher Date	2016-05-01
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright ©2016, Korean Society for Stem Cell Research
Subject Keyword	Stem cells Bone Marrow Mononuclear Cells Cerebral palsy Intrathecal injection
Content Type	Text
Resource Type	Article
Subject	Cell Biology Developmental Biology

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