NDLI: Visual Hallucinations and Amyloid Deposition in Parkinson's Disease Dementia: A Case Report.

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Visual Hallucinations and Amyloid Deposition in Parkinson's Disease Dementia: A Case Report.

Content Provider	Europe PMC
Author	Um, Yoo Hyun Kim, Tae-Won Jeong, Jong-Hyun Seo, Ho-Jun Han, Jin-Hee Hong, Seung-Chul Jung, Won-Sang Choi, Woo Hee Lee, Chang-Uk Lim, Hyun Kook
Copyright Year	2016
Abstract	Parkinson's disease dementia (PDD) is notorious for its debilitating clinical course and high mortality rates. Consequently, various attempts to investigate predictors of cognitive decline in Parkinson's disease (PD) have been made. Here we report a case of a 75-year-old female patient with PD who visited the clinic with complaints of recurrent visual hallucinations and cognitive decline, whose symptoms were ameliorated by the titration of rivastigmine. Imaging results showed pronounced diffuse cortical amyloid deposition evidenced by 18F-florbetaben amyloid positron emission tomography (PET) imaging. This observation suggests that pronounced amyloid deposition and visual hallucinations in PD patients could be clinically significant predictors of cognitive decline in PD patients. Future research should concentrate on accumulating more evidence for possible predictors of cognitive decline and their association with PD pathology that can enable an early intervention and standardized treatment in PDD patients.
ISSN	17383684
Journal	Psychiatry Investigation
Volume Number	13
PubMed Central reference number	PMC4878973
Issue Number	3
PubMed reference number	27247605
e-ISSN	19763026
DOI	10.4306/pi.2016.13.3.364
Language	English
Publisher	Korean Neuropsychiatric Association
Publisher Date	2016-05-18
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2016 Korean Neuropsychiatric Association
Subject Keyword	Parkinson's disease Dementia Amyloid imaging Cognitive decline
Content Type	Text
Resource Type	Article
Subject	Biological Psychiatry Psychiatry and Mental Health

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