NDLI: Multidimensional aspects of pain in myotonic dystrophies.

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Multidimensional aspects of pain in myotonic dystrophies.

Content Provider	Europe PMC
Author	Peric, Marina Peric, Stojan Rapajic, Nada Dobricic, Valerija Savic-Pavicevic, Dusanka Nesic, Ivana Radojicic, Svetlana Novakovic, Ivana Lavrnic, Dragana Rakocevic-Stojanovic, Vidosava
Abstract	To analyze the frequency and intensity of pain and its association with different characteristics of patients with myotonic dystrophy type 1 (DM1) and type 2 (DM2), 52 adult genetically confirmed DM1 and 44 DM2 patients completed the Brief Pain Inventory questionnaire (BPI).Frequency and average intensity of pain on numerical rating scale (0-10) were similar in DM1 and DM2 (88% vs. 86% and 4.6 ± 2.3 vs. 4.2 ± 1.8, respectively, p > 0.05). In DM1, average pain intensity showed strong association with longer duration of disease and inverse relation with cognition. In DM2, average pain intensity showed association with female gender and emotions. Average pain intensity correlated with Individualized Neuromuscular Quality of Life (INQoL) total score in both DM1 (rho = +0.30, p < 0.05) and DM2 patients (rho = +0.61, p < 0.01).In conclusion, the majority of DM1 and DM2 patients have mild to moderate pain. Our results open new opportunities for behavioral and cognitive interventions.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4859081&blobtype=pdf
ISSN	11282460
Journal	Acta Myologica [Acta Myol]
Volume Number	34
PubMed Central reference number	PMC4859081
Issue Number	2-3
PubMed reference number	27199540
Language	English
Publisher	Pacini Editore SRL
Publisher Date	2015-12-01
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License, which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way. For details, please refer to http://creativecommons.org/licenses/by-nc-nd/3.0/ The journal and the individual contributions contained in it are protected by the copyright of Gaetano Conte Academy, Naples, Italy
Subject Keyword	myotonic dystrophy type 1 myotonic dystrophy type 2 pain quality of life
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine

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