NDLI: Reflectance confocal microscopy and dermoscopy for <i>in vivo</i>, non-invasive skin imaging of superficial basal cell carcinoma.

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Reflectance confocal microscopy and dermoscopy for in vivo, non-invasive skin imaging of superficial basal cell carcinoma.

Content Provider	Europe PMC
Author	GHITA, MIHAELA A. CARUNTU, CONSTANTIN ROSCA, ADRIAN E. KALESHI, HARILLAQ CARUNTU, ANA MORARU, LILIANA DOCEA, ANCA OANA ZURAC, SABINA BODA, DANIEL NEAGU, MONICA SPANDIDOS, DEMETRIOS A. TSATSAKIS, ARISTIDIS M.
Copyright Year	2016
Abstract	Superficial basal cell carcinoma (sBCC) is the second most frequent histological type of basal cell carcinoma (BCC), usually requiring a skin biopsy to confirm the diagnosis. It usually appears on the upper trunk and shoulders as erythematous and squamous lesions. Although it has a slow growth and seldom metastasizes, early diagnosis and management are of crucial importance in preventing local invasion and subsequent disfigurement. Dermoscopy is nowadays an indispensable tool for the dermatologist when evaluating skin tumors. Reflectance confocal microscopy (RCM) is a novel imaging technique that allows the non-invasive, in vivo quasi-microscopic morphological and dynamic assessment of superficial skin tumors. Moreover, it offers the advantage of performing infinite repeatable determinations to monitor disease progression and non-surgical treatment for sBCC. Herein, we present three lesions of sBCC evaluated using in vivo and non-invasive imaging techniques, emphasizing the usefulness of combining RCM with dermoscopy for increasing the diagnostic accuracy of sBCC.
ISSN	17921074
Journal	Oncology Letters
Volume Number	11
PubMed Central reference number	PMC4840988
Issue Number	5
PubMed reference number	27123056
e-ISSN	17921082
DOI	10.3892/ol.2016.4354
Language	English
Publisher	D.A. Spandidos
Publisher Date	2016-03-21
Access Restriction	Open
Rights License	This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. Copyright: © Ghita et al.
Subject Keyword	superficial basal cell carcinoma dermoscopy reflectance confocal microscopy non-invasive in vivo skin imaging
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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