High therapeutic potential of Spilanthes acmella: A review.

Content Provider	Europe PMC
Author	Prachayasittikul, Veda Prachayasittikul, Supaluk Ruchirawat, Somsak Prachayasittikul, Virapong
Copyright Year	2013
Abstract	Spilanthes acmella, a well known antitoothache plant with high medicinal usages, has been recognized as an important medicinal plant and has an increasingly high demand worldwide. From its traditional uses in health care and food, extensive phytochemical studies have been reported. This review provides an overview and general description of the plant species, bioactive metabolites and important pharmacological activities including the preparation, purification and in vitro large-scale production. Structure-activity relationships of the bioactive compounds have been discussed. Considering data from the literature, it could be demonstrated that S. acmella possesses diverse bioactive properties and immense utilization in medicine, health care, cosmetics and as health supplements. As a health food, it is enriched with high therapeutic value with high potential for further development.
Journal	EXCLI Journal
Volume Number	12
PubMed Central reference number	PMC4827075
PubMed reference number	27092032
e-ISSN	16112156
Language	English
Publisher	Leibniz Research Centre for Working Environment and Human Factors
Publisher Date	2013-04-04
Access Restriction	Open
Rights License	This is an Open Access article distributed under the following Assignment of Rights http://www.excli.de/documents/assignment_of_rights.pdf. You are free to copy, distribute and transmit the work, provided the original author and source are credited. Copyright © 2013 Prachayasittikul et al.
Subject Keyword	Spilanthes acmella bioactive metabolites bioactivities structure-activity relationships in vitro production
Content Type	Text
Resource Type	Article
Subject	Drug Discovery Pharmacology Animal Science and Zoology Molecular Medicine