Effects of poly(L-lactide-ε-caprolactone) and magnesium hydroxide additives on physico-mechanical properties and degradation of poly(L-lactic acid).

Content Provider	Europe PMC
Author	Kang, Eun Young Lih, Eugene Kim, Ik Hwan Joung, Yoon Ki Han, Dong Keun
Abstract	BackgroundBiodegradable poly(L-lactic acid) (PLLA) is one of the most widely used polymer in biomedical devices, but it still has limitations such as inherent brittleness and acidic degradation products. In this work, PLLA blends with poly(L-lactide-ε-caprolactone) (PLCL) and Mg(OH)2 were prepared by the thermal processing to improve their physico-mechanical and thermal properties. In addition, the neutralizing effect of Mg(OH)2 was evaluated by degradation study.ResultsThe elongation of PLLA remarkably increased from 3 to 164.4 % and the glass transition temperature (Tg) of PLLA was slightly reduced from 61 to 52 °C by adding PLCL additive. Mg(OH)2 in polymeric matrix not only improved the molecular weight reduction and mechanical strength of PLLA, but also neutralized the acidic byproducts generated during polyester degradation.ConclusionsTherefore, the results demonstrated that the presence of PLCL and Mg(OH)2 additives in PLLA matrix could prevent the thermal decomposition and control degradation behavior of polyester.
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Journal	Biomaterials Research [Biomater Res]
Volume Number	20
DOI	10.1186/s40824-016-0054-6
PubMed Central reference number	PMC4791761
PubMed reference number	26981259
e-ISSN	20557124
Language	English
Publisher	BioMed Central
Publisher Date	2016-03-15
Publisher Place	London
Access Restriction	Open
Rights License	Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. © Kang et al. 2016
Subject Keyword	Poly(L-lactic acid) Poly(L-lactide-ε-caprolactone) Magnesium hydroxide Thermal decomposition Neutralization
Content Type	Text
Resource Type	Article
Subject	Ceramics and Composites Biomaterials Medicine Biomedical Engineering