Transdiagnostic Treatment of Co-occurrence of Anxiety and Depressive Disorders based on Repetitive Negative Thinking: A Case Series.

Content Provider	Europe PMC
Author	Akbari, Mehdi Roshan, Rasool Shabani, Amir Fata, Ladan Shairi, Mohamad Reza Zarghami, Firouzeh
Abstract	Objective: The transdiagnostic cognitive behavioral treatments for treating the coexistence of anxiety and mood disorders received useful empirical supports in the recent years. However, these treatments still have moderate efficacy. Following the improvements and developments in transdiagnostic protocols and considering the importance of repetitive negative thinking as a core transdiagnostic factor in emotional disorders, this study examined a new form of transdiagnostic treatment based on Repetitive Negative Thinking (TTRNT) of co-occurrence of anxiety and depressive disorders.Methods: Treatment efficacy was assessed using single case series with multiple baselines. Three patients meeting the criteria for co-occurrence of anxiety and depressive disorders were selected using the Anxiety Disorders Interview Schedule for DSM-IV. The patients were treated individually for 12 weekly sessions. Participants completed the standardized outcome measures during the baseline, treatment and one-month follow-up.Results: At post-treatment, all participants showed significant clinical changes on a range of standardized outcome measures, and these gains were largely maintained through the one-month follow-up both in the principle and co-principal diagnosis.Conclusions: Although the results of this preliminary investigation indicated that TTRNT could be a time effective and efficient treatment for individuals with co-occurrence of anxiety and depressive disorders, further controlled clinical trials are necessary to examine this new treatment approach.
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ISSN	17354587
Journal	Iranian Journal of Psychiatry [Iran J Psychiatry]
Volume Number	10
PubMed Central reference number	PMC4749690
Issue Number	3
PubMed reference number	26877754
e-ISSN	20082215
Language	English
Publisher	Psychiatry & Psychology Research Center, Tehran University of Medical Sciences
Publisher Date	2015-06-01
Publisher Place	Tehran, Iran
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © Psychiatry & Psychology Research Center, Tehran University of Medical Sciences
Subject Keyword	Transdiagnostic Treatment Repetitive Negative Thinking Anxiety Depression.
Content Type	Text
Resource Type	Article
Subject	Psychiatry and Mental Health