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Magnetic Resonance Spectroscopy: Principles and Techniques: Lessons for Clinicians.
| Content Provider | Europe PMC |
|---|---|
| Author | Tognarelli, Joshua M. Dawood, Mahvish Shariff, Mohamed I.F. Grover, Vijay P.B. Crossey, Mary M.E. Cox, I. Jane Taylor-Robinson, Simon D. McPhail, Mark J.W. |
| Copyright Year | 2015 |
| Abstract | Magnetic resonance spectroscopy (MRS) provides a non-invasive ‘window’ on biochemical processes within the body. Its use is no longer restricted to the field of research, with applications in clinical practice increasingly common. MRS can be conducted at high magnetic field strengths (typically 11–14 T) on body fluids, cell extracts and tissue samples, with new developments in whole-body magnetic resonance imaging (MRI) allowing clinical MRS at the end of a standard MRI examination, obtaining functional information in addition to anatomical information. We discuss the background physics the busy clinician needs to know before considering using the technique as an investigative tool. Some potential applications of hepatic and cerebral MRS in chronic liver disease are also discussed. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4723643&blobtype=pdf |
| ISSN | 09736883 |
| Volume Number | 5 |
| DOI | 10.1016/j.jceh.2015.10.006 |
| PubMed Central reference number | PMC4723643 |
| Issue Number | 4 |
| PubMed reference number | 26900274 |
| Journal | Journal of Clinical and Experimental Hepatology [J Clin Exp Hepatol] |
| e-ISSN | 22133453 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-11-12 |
| Access Restriction | Open |
| Rights License | © 2015, INASL. |
| Subject Keyword | CPMG, Carr-Purcell-Meiboom-Gill sequence CSI, chemical shift imaging FID, free induction decay K, Kelvin KEGG, Kyoto Encyclopedia for Genes and Genomes MR, magnetic resonance MRI, magnetic resonance imaging MRS, magnetic resonance spectroscopy MSEA, metabolite set enrichment analysis NMR, nuclear magnetic resonance NOESY, nuclear Overhauser enhancement spectroscopy PC, principal components PCA, principal components analysis PLS-DA, partial least squared discriminant analysis PRESS, point-resolved spectroscopy STEAM, stimulated echo acquisition mode T, Tesla T1, spin-lattice relaxation T2, spin-spin relaxation TE, echo time TMAO, trimethylamine N-oxide TR, repetition time nuclear magnetic resonance magnetic resonance imaging magnetic resonance spectroscopy metabolomics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hepatology |