Diagnostic Accuracy of Obstructive Airway Adult Test for Diagnosis of Obstructive Sleep Apnea.

Content Provider	Europe PMC
Author	Gasparini, Giulio Vicini, Claudio De Benedetto, Michele Salamanca, Fabrizio Sorrenti, Giovanni Romandini, Mario Bosi, Marcello Saponaro, Gianmarco Foresta, Enrico Laforì, Andreina Meccariello, Giuseppe Bianchi, Alessandro Toraldo, Domenico Maurizio Campanini, Aldo Montevecchi, Filippo Rizzotto, Grazia Cervelli, Daniele Moro, Alessandro Arigliani, Michele Gobbi, Riccardo Pelo, Sandro
Copyright Year	2015
Abstract	Rationale. The gold standard for the diagnosis of Obstructive Sleep Apnea (OSA) is polysomnography, whose access is however reduced by costs and limited availability, so that additional diagnostic tests are needed. Objectives. To analyze the diagnostic accuracy of the Obstructive Airway Adult Test (OAAT) compared to polysomnography for the diagnosis of OSA in adult patients. Methods. Ninety patients affected by OSA verified with polysomnography (AHI ≥ 5) and ten healthy patients, randomly selected, were included and all were interviewed by one blind examiner with OAAT questions. Measurements and Main Results. The Spearman rho, evaluated to measure the correlation between OAAT and polysomnography, was 0.72 (p < 0.01). The area under the ROC curve (95% CI) was the parameter to evaluate the accuracy of the OAAT: it was 0.91 (0.81–1.00) for the diagnosis of OSA (AHI ≥ 5), 0.90 (0.82–0.98) for moderate OSA (AHI ≥ 15), and 0.84 (0.76–0.92) for severe OSA (AHI ≥ 30). Conclusions. The OAAT has shown a high correlation with polysomnography and also a high diagnostic accuracy for the diagnosis of OSA. It has also been shown to be able to discriminate among the different degrees of severity of OSA. Additional large studies aiming to validate this questionnaire as a screening or diagnostic test are needed.
ISSN	23146133
Journal	Biomed Research International
Volume Number	2015
PubMed Central reference number	PMC4618120
PubMed reference number	26636102
e-ISSN	23146141
DOI	10.1155/2015/915185
Language	English
Publisher	Hindawi
Publisher Date	2015-10-08
Access Restriction	Open
Rights License	This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2015 Giulio Gasparini et al.
Content Type	Text
Resource Type	Article
Subject	Immunology and Microbiology Medicine Biochemistry, Genetics and Molecular Biology