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Co-enhancement of fluorescence and singlet oxygen generation by silica-coated gold nanorods core-shell nanoparticle.
| Content Provider | Europe PMC |
|---|---|
| Author | Ke, Xuebin Wang, Dong Chen, Changqing Yang, Anqi Han, Yu Ren, Lei Li, Donghui Wang, Hongjun |
| Abstract | Metal-enhanced fluorescence (MEF) as a newly recognized technology has been attracting considerable attention and is widely used in fluorescence-based technology. In this paper, we reported a novel distance-dependent MEF and metal-enhanced singlet oxygen generation phenomenon based on silica-coated gold nanorods (AuNRs@SiO2) core-shell structure with tetra-substituted carboxyl aluminum phthalocyanine (AlC4Pc) that serve as both fluorophore and photosensitizer. When the AlC4Pc was linked on the surface of AuNRs@SiO2, the fluorescence intensity and singlet oxygen productivity varied with the thickness difference of silica shell from 2.1 to 28.6 nm. The co-enhancement effect reached the maximum of 7-fold and 2.1-fold, respectively, when the separation distance was 10.6 nm. These unique characteristics make the prepared core-shell nanoparticles promising for MEF-based biological imaging and photodynamics therapy. |
| ISSN | 19317573 |
| Journal | Nanoscale Research Letters |
| Volume Number | 9 |
| PubMed Central reference number | PMC4493993 |
| Issue Number | 1 |
| PubMed reference number | 26088999 |
| e-ISSN | 1556276X |
| DOI | 10.1186/1556-276x-9-666 |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2014-12-10 |
| Publisher Place | New York |
| Access Restriction | Open |
| Rights License | This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. © Ke et al.; licensee Springer. 2014 |
| Subject Keyword | Surface plasmon resonance Silica-coated gold nanorods Metal-enhanced fluorescence Metal-enhanced singlet oxygen generation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Condensed Matter Physics Materials Science |