Cardiovascular and All-Cause Mortality Over a 23-Year Period Among Chinese With Newly Diagnosed Diabetes in the Da Qing IGT and Diabetes Study.

Content Provider	Europe PMC
Author	An, Yali Zhang, Ping Wang, Jinping Gong, Qiuhong Gregg, Edward W. Yang, Wenying Li, Hui Zhang, Bo Shuai, Ying Chen, Yanyan Engelgau, Michael M. Cheng, Yiling Hu, Yinghua Bennett, Peter H. Li, Guangwei
Copyright Year	2015
Abstract	OBJECTIVEDespite its growing prevalence in China, the extent to which diabetes leads to excess cardiovascular disease (CVD) mortality and all-cause mortality is unclear.RESEARCH DESIGN AND METHODSWe compared death rates and causes of death among 630 people with newly diagnosed diabetes (NDD) and 519 with normal glucose tolerance (NGT) who, in 1986, were identified as a result of screening 110,660 adults aged 25–74 years for diabetes in Da Qing, China.RESULTSDuring 23 years of follow-up, 338 (56.5%) participants with NDD and 100 (20.3%) with NGT died. CVD was the predominant cause of death in those with diabetes (47.5% in men and 49.7% in women), almost half of which was due to stroke (52.3% in men and 42.3% in women). The age-standardized incidence of all-cause death was three times as high in those with NDD as in those with NGT with incidences (per 1,000 person-years) of 36.9 (95% CI 31.5–42.3) vs. 13.3 (10.2–16.5) in men (P < 0.0001) and 27.1 (22.9–31.4) vs. 9.2 (7.8–10.6) in women (P < 0.0001). The incidence of CVD deaths in men and women with NDD (17.5 [13.8–21.2] vs. 13.5 [10.5–16.5]) did not differ significantly. Significantly higher death rates attributable to renal disease and infection were also found in the NDD group.CONCLUSIONSDiabetes is associated with a substantially increased risk of death in Chinese adults, especially from CVD, almost half of which is due to stroke.
Page Count	7
ISSN	01495992
Volume Number	38
PubMed Central reference number	PMC4477333
Issue Number	7
PubMed reference number	25887356
Journal	Diabetes Care
e-ISSN	19355548
DOI	10.2337/dc14-2498
Language	English
Publisher	American Diabetes Association
Publisher Date	2015-04-17
Access Restriction	Open
Rights License	© 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
Content Type	Text
Resource Type	Article
Subject	Endocrinology, Diabetes and Metabolism Advanced and Specialized Nursing Internal Medicine