Comparison of primary coronary percutaneous coronary intervention between Diabetic Men and Women with acute myocardial infarction.

Content Provider	Europe PMC
Author	Liu, Heng-Liang Liu, Yang Hao, Zhen-Xuan Geng, Guo-Ying Zhang, Zhi-Fang Jing, Song-Bin Ba, Ning Guo, Wei
Copyright Year	2015
Abstract	Objective:This study aimed to explore the short-term efficacy and safety of primary percutaneous coronary intervention (PCI) in female diabetic patients complicated with acute myocardial infarction (AMI).Methods:A total of 169 diabetic patients with AMI who underwent primary PCI were selected and divided into group A (52 females) and group B (117 males). The clinical data, characteristics of coronary artery lesions, lengths of hospital stay, and incidences of complications were then compared between two groups.Results:The average age, history of hyperlipidemia, double branch lesions, triple branch lesions, and left main lesions were significantly higher in group A than in group B (P < 0.05). Smoking history, PCI history, and pre-infarction angina were distinctly lower in group A than in group B (P < 0.05). Thrombolysis in myocardial infarction 3 (TIMI3) flow and TIMI myocardial perfusion grade 3 (TMPG3) after PCI were markedly lower in group A than in group B (P < 0.001). Group A had a higher incidence of complications, such as severe arrhythmia, cardiac function Killip III/IV, cardiogenic shock, major, moderate and mild bleed event, as well as a 30-day mortality rate, compared with group B (P < 0.05).Conclusion:In summary, our study demonstrated that female diabetic patients with AMI had lower TIMI3 flow and TMPG3 following PCI than male patients, while there was higher incidence of complications and 30-day mortality rate. Therefore, more attention should be paid to the therapy of diabetic women with acute myocardial infarction as well as the control of risk factors.
ISSN	1682024X
Volume Number	31
PubMed Central reference number	PMC4476354
Issue Number	2
PubMed reference number	26101503
Journal	Pakistan Journal of Medical Sciences [Pak J Med Sci]
e-ISSN	1681715X
DOI	10.12669/pjms.312.6646
Language	English
Publisher	Professional Medical Publications
Publisher Date	2015-03-01
Publisher Place	Pakistan
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright: © Pakistan Journal of Medical Sciences
Subject Keyword	Acute myocardial infarction Diabetes mellitus primary percutaneous coronary intervention Female
Content Type	Text
Resource Type	Article
Subject	Medicine