NDLI: Primary non-hodgkin lymphoma of the stomach: clinicopathological characteristics and prognostic factors in Iranian patients.

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Primary non-hodgkin lymphoma of the stomach: clinicopathological characteristics and prognostic factors in Iranian patients.

Content Provider	Europe PMC
Author	Hosseini, Sare Dehghan, Parvaneh
Copyright Year	2014
Abstract	BackgroundPrimary Gastric Lymphoma (PGL) is an uncommon malignancy with various histological subtypes and treatment outcomes. The aim of this study was to investigate the potential prognostic factors and clinicopathological characteristics of Iranian patients with PGL.MethodsThe clinicopathological characteristics of 60 patients with PGL were retrospectively reviewed from 2001 to 2012. The patients underwent various combinations of chemotherapy, radiotherapy, and surgery. We evaluated multiple potential prognostic factors and their associations with patient survival rate.ResultsAccording to the results, Diffuse Large B-cell Lymphoma (DLBCL) and Mucosa-Associated Lymphoid Tissue (MALT) were two predominant histological subtypes. The majority of cases were diagnosed with stage I tumor in the distal part of the stomach. The 5-year disease-free survival (DFS) and overall survival (OS) rates were 60% and 70%, respectively. It was revealed that poor World Health Organization (WHO) performance status, presence of B symptoms, and International Prognostic Index (IPI) score≥3 were significantly associated with decreased patient survival.ConclusionMost of the patients with PGL in early stage have a favorable prognosis.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4307104&blobtype=pdf
ISSN	20082398
Journal	Iranian Journal of Cancer Prevention [Iran J Cancer Prev]
Volume Number	7
PubMed Central reference number	PMC4307104
Issue Number	4
PubMed reference number	25628842
e-ISSN	20082401
Language	English
Publisher	Cancer Research Center, Shahid Beheshti University of Medical Sciences
Publisher Date	2014-01-01
Access Restriction	Open
Rights License	This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. © 2014 Cancer Research Center, Shahid Beheshti University of Medical Sciences
Subject Keyword	Non-Hodgkin lymphoma stomach prognostic factor overall survival rate
Content Type	Text
Resource Type	Article
Subject	Genetics Cancer Research Genetics (clinical) Oncology

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