Anti-aging Potential of Extracts Prepared from Fruits and Medicinal Herbs Cultivated in the Gyeongnam Area of Korea.

Content Provider	Europe PMC
Author	Shon, Myung-Soo Lee, Yunjeong Song, Ji-Hye Park, Taehyun Lee, Jun Kyoung Kim, Minju Park, Eunju Kim, Gyo-Nam
Copyright Year	2014
Abstract	Many recent studies have focused on maintaining a healthy life by preventing and/or postponing the aging process. Numerous studies have reported that continuous exposure to reactive oxygen species can stimulate skin aging and that excessive accumulation of fat can cause an impaired skin barrier and tissue structure alterations. Thus, the maintenance of antioxidant homeostasis and the suppression of adipose accumulation are important strategies for skin anti-aging. Here, we prepared three types of extracts [whole juice, acetone-perchloric acid (PCA), and ethanol] from 20 fruits and medicinal herbs native to the Gyeongnam area of Korea. The total phenolic content of each extract was analyzed, and we observed higher total phenolic contents in the medicinal herbs. Consistent with this, the results of the oxygen radical absorbance activity capacity assay indicated that the in vitro antioxidant activities of the medicinal herb extracts were stronger than those of the fruit extracts. The fruits and medicinal herbs had strong effects on cell-based systems, including H2O2-induced oxidative stress in human keratinocytes and 3T3-L1 lipid accumulation. Nishimura Wase persimmon, Taishu persimmon, wrinkled giant hyssop, sweet wormwood, Chinese cedar, red perilla, tan shen, hiyodori-jogo, and cramp bark may be natural anti-aging materials with effective antioxidant and anti-adipogenic activities. Taken together, our findings may provide scientific evidence supporting the development of functional foods and nutraceuticals from fruits and medicinal herbs.
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ISSN	22871098
Journal	Preventive Nutrition and Food Science [Prev Nutr Food Sci]
Volume Number	19
DOI	10.3746/pnf.2014.19.3.178
PubMed Central reference number	PMC4195623
Issue Number	3
PubMed reference number	25320715
e-ISSN	22878602
Language	English
Publisher	The Korean Society of Food Science and Nutrition
Publisher Date	2014-09-01
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2014 by The Korean Society of Food Science and Nutrition. All rights Reserved.
Subject Keyword	fruits medicinal herbs anti-aging skin gyeongnam
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Food Science