NDLI: Alteration of lipid parameters in patients with subclinical hypothyroidism.

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Alteration of lipid parameters in patients with subclinical hypothyroidism.

Content Provider	Europe PMC
Author	Laway, Bashir Ahmad War, Fayaz Ahmad Shah, Sonaullah Misgar, Raiz Ahmad Kumar Kotwal, Suman
Copyright Year	2014
Abstract	Background:Overt hypothyroidism is associated with abnormalities of lipid metabolism, but conflicting results regarding the degree of lipid changes in subclinical hypothyroidism (SCH) exist.Objectives:The aim of this study was to assess differences in lipid profile parameters between subjects with and without SCH in a north Indian population.Patients and Methods:Serum lipid parameters of 70 patients with subclinical hypothyroidism and 100 age and sex matched euthyroid controls were evaluated in a cross-sectional study.Results:Mean serum total cholesterol (TC), triglycerides (TG) and very low-density cholesterol (VLDL) were significantly higher in patients with SCH than controls (P < 0.05). Mean TC, TG and low-density cholesterol (LDL) concentrations were higher in patients with serum thyroid stimulating hormone (TSH) greater than 10 mU/L than those with serum TSH equal to or less than 10 mU/L, but this difference was not statistically significant. No association was found between serum high-density cholesterol (HDL-C) concentration and serum TSH level.Conclusions:High TC, TG and VLDL were observed in our patients with SCH.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4166037&blobtype=pdf
ISSN	1726913X
Journal	International Journal of Endocrinology and Metabolism [Int J Endocrinol Metab]
Volume Number	12
DOI	10.5812/ijem.17496
PubMed Central reference number	PMC4166037
Issue Number	3
PubMed reference number	25237326
e-ISSN	17269148
Language	English
Publisher	Kowsar
Publisher Date	2014-07-01
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2014, Research Institute For Endocrine Sciences and Iran Endocrine Society; Published by Kowsar Corp.
Subject Keyword	Hypothyroidism Lipids
Content Type	Text
Resource Type	Article
Subject	Endocrinology, Diabetes and Metabolism

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