NDLI: Genome analysis of 17 extensively drug-resistant strains reveals new potential mutations for resistance.

Content Provider	Europe PMC
Author	Guio, H. Tarazona, D. Galarza, M. Borda, V. Curitomay, R.
Copyright Year	2014
Abstract	We report the whole-genome sequence of an extensively drug-resistant (XDR) tuberculosis (TB) strain of Latin American–Mediterranean (LAM) lineage. This strain is phenotypically resistant to aminoglycosides, but carries no related mutations in rrs, tlyA, and eis. Through genome analysis comparison with 16 XDR strains, we found 218 non-synonymous single nucleotide polymorphisms (SNPs) shared that could confer resistance.
Page Count	2
Journal	Genome Announcements
Volume Number	2
PubMed Central reference number	PMC4118072
Issue Number	4
PubMed reference number	25081269
e-ISSN	21698287
DOI	10.1128/genomea.00759-14
Language	English
Publisher	American Society for Microbiology
Publisher Date	2014-07-31
Publisher Place	1752 N St., N.W., Washington, DC
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license. Copyright © 2014 Guio et al.
Content Type	Text
Resource Type	Article
Subject	Genetics Molecular Biology

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