NDLI: Evaluation of antibacterial, antifungal, and antioxidant activities of safflower natural dyes during flowering.

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Evaluation of antibacterial, antifungal, and antioxidant activities of safflower natural dyes during flowering.

Content Provider	Europe PMC
Author	Salem, Nidhal Msaada, Kamel Elkahoui, Salem Mangano, Giuseppe Azaeiz, Sana Ben Slimen, Imen Kefi, Sarra Pintore, Giorgio Limam, Ferid Marzouk, Brahim
Copyright Year	2014
Abstract	Two Carthamus tinctorius varieties (Jawhara and 104) were studied in order to investigate their natural dyes contents and biological activities. Obtained results showed that quinochalcone contents and antioxidant activities varied considerably as function of flowering stages. So flowers at fructification stage contained the highest carthamin content with the strongest antioxidant capacity with all assays (FRAP, DPPH, and chelating power methods). In parallel, we showed a decrease in the content of precarthamin. The quantitative variation of these molecules could be due to colour change of C. tinctorius flowers. Correlation analysis indicated that the ABTS method showed the highest correlation coefficients with carthamin and precarthamin contents, that is, 0.886 and 0.973, respectively. Concerning the regional effect, the contents of precarthamin and carthamin varied significantly (P < 0.05) at studied regions with the optimum production given by samples of Beja (902.41 μg/g DW and 42.05 μg/g DW, respectively, at flowering stage). During flowering, the antimicrobial activity of these two natural dyes increased where the maximum inhibitory effect mentioned with carthamin mainly against E. coli (iz = 25.89 mm) at fructification stage. Therefore, the increased frequency of resistance to commonly used antibiotics leads to the search for new effective natural drugs at food and pharmaceutical industries.
ISSN	23146133
Journal	Biomed Research International
Volume Number	2014
PubMed Central reference number	PMC4090561
PubMed reference number	25045699
e-ISSN	23146141
DOI	10.1155/2014/762397
Language	English
Publisher	Hindawi
Publisher Date	2014-06-22
Access Restriction	Open
Rights License	This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2014 Nidhal Salem et al.
Content Type	Text
Resource Type	Article
Subject	Immunology and Microbiology Medicine Biochemistry, Genetics and Molecular Biology

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