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Interaction of light regimes and circadian clocks modulate timing of pre-adult developmental events in Drosophila.
| Content Provider | Europe PMC |
|---|---|
| Author | Yadav, Pankaj Thandapani, Madhumohan Sharma, Vijay Kumar |
| Copyright Year | 2014 |
| Abstract | BackgroundCircadian clocks have been postulated to regulate development time in several species of insects including fruit flies Drosophila melanogaster. Previously we have reported that selection for faster pre-adult development reduces development time (by ~19 h or ~11%) and clock period (by ~0.5 h), suggesting a role of circadian clocks in the regulation of development time in D. melanogaster. We reasoned that these faster developing flies could serve as a model to study stage-specific interaction of circadian clocks and developmental events with the environmental light/dark (LD) conditions. We assayed the duration of three pre-adult stages in the faster developing (FD) and control (BD) populations under a variety of light regimes that are known to modulate circadian clocks and pre-adult development time of Drosophila to examine the role of circadian clocks in the timing of pre-adult developmental stages.ResultsWe find that the duration of pre-adult stages was shorter under constant light (LL) and short period light (L)/dark (D) cycles (L:D = 10:10 h; T20) compared to the standard 24 h day (L:D = 12:12 h; T24), long LD cycles (L:D = 14:14 h; T28) and constant darkness (DD). The difference in the duration of pre-adult stages between the FD and BD populations was significantly smaller under the three LD cycles and LL compared to DD, possibly due to the fact that clocks of both FD and BD flies are driven at the same pace in the three LD regimes owing to circadian entrainment, or are rendered dysfunctional under LL.ConclusionsThese results suggest that interaction between light regimes and circadian clocks regulate the duration of pre-adult developmental stages in fruit flies D. melanogaster. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4040135&blobtype=pdf |
| Journal | BMC Developmental Biology [BMC Dev Biol] |
| Volume Number | 14 |
| PubMed Central reference number | PMC4040135 |
| PubMed reference number | 24885932 |
| e-ISSN | 1471213X |
| DOI | 10.1186/1471-213x-14-19 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2014-05-16 |
| Access Restriction | Open |
| Rights License | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Copyright © 2014 Yadav et al.; licensee BioMed Central Ltd. |
| Subject Keyword | Circadian clocks Faster development Light regimes Selection Development time Pre-adult stages |
| Content Type | Text |
| Resource Type | Article |
| Subject | Developmental Biology |
