NDLI: Primary Burkitt's lymphoma of the thyroid without Epstein-Barr virus infection: A case report and literature review.

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Primary Burkitt's lymphoma of the thyroid without Epstein-Barr virus infection: A case report and literature review.

Content Provider	Europe PMC
Author	ZHANG, LIYING GAO, LANXIANG LIU, GUANG WANG, LUPING XU, CHUNWEI LI, LIN TIAN, YUWANG FENG, HUIRU GUO, ZHE
Copyright Year	2014
Abstract	Primary thyroid lymphomas are rare, and the majority are B-cell lymphoma. Primary Burkitt’s lymphoma (BL) of the thyroid is much less common than the other types of lymphoma. The current study presents the case of an eight-year-old male with a mass in the right lobe of the thyroid, which was detected by B-ultrasound. The patient was diagnosed with BL by immunohistochemistry, fluorescence in situ hybridization analysis of MYC (8q24) and immunoglobulin rearrangement assays. Furthermore, subsequent positron emission tomography-computed tomography scans revealed no abnormal metabolites in the left lobe of the thyroid or in other parts of the body following surgery. The patient underwent alternate R-B-NHL-BFM-90-A and R-B-NHL-BFM-90-B treatment for four cycles each following the thyroidectomy. The patient is well and remains free of disease recurrence following almost four years follow-up. The present study discusses this rare case of primary BL of the thyroid and presents a review of the literature. This case report provides evidence that the immediate diagnosis and treatment of primary Burkitt’s lymphoma of the thyroid is likely to improve patient outcome.
ISSN	17921074
Journal	Oncology Letters
Volume Number	7
PubMed Central reference number	PMC3997736
Issue Number	5
PubMed reference number	24765169
e-ISSN	17921082
DOI	10.3892/ol.2014.1941
Language	English
Publisher	D.A. Spandidos
Publisher Date	2014-03-05
Access Restriction	Open
Rights License	This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. Copyright © 2014, Spandidos Publications
Subject Keyword	Epstein-Barr virus fluorescence in situ hybridization immunoglobulin rearrangement assay Burkitt’s lymphoma thyroid
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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