Prevalence, clinical features, and outcome of pseudomonas bacteremia in under-five diarrheal children in bangladesh.

Content Provider	Europe PMC
Author	Akram, Farhana Pietroni, Mark A. C. Bardhan, Pradip Kumar Bibi, Samira Chisti, Mohammod Jobayer
Copyright Year	2014
Abstract	We sought to evaluate the prevalence, associated factors, and outcome of under-five diarrheal children with either sex having Pseudomonas bacteremia. A retrospective chart review of under-five diarrheal children admitted to the Dhaka Hospital of the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), from January 2011 to December 2011 was performed using an online hospital management system. Children with Pseudomonas bacteremia constituted the cases (n = 31), and the controls (n = 124), without Pseudomonas bacteremia, were randomly selected. The prevalence of Pseudomonas bacteremia was 1% (31/5,179). The Pseudomonas was multidrug resistant but was 84% sensitive to ceftazidime and 100% to imipenem. The case-fatality rate was significantly higher among the cases than the controls (26% versus 5%; P = 0.003). In logistic regression analysis, after adjusting for potential confounders such as severe wasting, severe underweight, severe pneumonia, and young age (11.71 (4.0, 18.0) months), the cases more often presented with absent peripheral pulses in absence of dehydration (95% CI = 2.31–24.45) on admission. This finding underscores the importance of early identification of this simple clinical sign to ensure prompt management including fluid resuscitation and broad spectrum antibiotics to help reduce morbidity and mortality in such children, especially in resource-poor settings.
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ISSN	20907478
Volume Number	2014
DOI	10.1155/2014/469758
PubMed Central reference number	PMC3966484
PubMed reference number	24734204
Journal	ISRN Microbiology [ISRN Microbiol]
e-ISSN	20907486
Language	English
Publisher	Hindawi Publishing Corporation
Publisher Date	2014-03-09
Access Restriction	Open
Rights License	This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2014 Farhana Akram et al.
Content Type	Text
Resource Type	Article
Subject	Microbiology (medical)