JAK-STAT signaling and myocardial glucose metabolism.

Content Provider	Europe PMC
Author	Frias, Miguel A Montessuit, Christophe
Copyright Year	2013
Abstract	JAK-STAT signaling occurs in virtually every tissue of the body, and so does glucose metabolism. In this review, we summarize the regulation of glucose metabolism in the myocardium and ponder whether JAK-STAT signaling participates in this regulation. Despite a paucity of data directly pertaining to cardiac myocytes, we conclude that JAK-STAT signaling may contribute to the development of insulin resistance in the myocardium in response to various hormones and cytokines.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3876426&blobtype=pdf
ISSN	21623988
Volume Number	2
DOI	10.4161/jkst.26458
PubMed Central reference number	PMC3876426
Issue Number	4
PubMed reference number	24416656
Journal	JAK-STAT
e-ISSN	21623996
Language	English
Publisher	Landes Bioscience
Publisher Date	2013-09-27
Access Restriction	Open
Rights License	This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. Copyright © 2013 Landes Bioscience
Subject Keyword	cardiac myocytes glucose metabolism insulin insulin resistance Janus kinase JAK myocardium signal transducer and activator of transcription STAT suppressor of cytokine signaling SOCS
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical)