NDLI: Novel antibacterial activity of lactococcus lactis subspecies lactis z11 isolated from zabady.

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Novel antibacterial activity of lactococcus lactis subspecies lactis z11 isolated from zabady.

Content Provider	Europe PMC
Author	Enan, Gamal Abdel-Shafi, Seham Ouda, Sahar Negm, Sally
Copyright Year	2013
Abstract	The purpose of this study was to select and characterize a probiotic bacterium with distinctive antimicrobial activities. In this respect, Lactococcus lactis subspecies lactis Z11 (L. lactis Z11) isolated from Zabady (Arabian yoghurt) inhibited other strains of lactic acid bacteria and some food-born pathogens including Listeria monocytogenes, Bacillus cereus and staphylococcus aureus. The inhibitory activity of cell free supernatant (CFS) of L. lactis Z11 isolated from zabady was lost by proteolytic enzymes, heat resistant. Consequently, the active substance(s) of CFS was characterized as a bacteriocin. This bacteriocin has been shown to consist of protein but has no lipidic or glucidic moieties in its active molecule. Its activity was stable in the pH range 2.0 to 7.0 and was not affected by organic solvents. The L. lactis Z11 bacteriocin was produced in CFS throughout the mide to the late exponential phase of growth of the producer organism and maximum bacteriocin production was obtained at initial pH 6.5 at incubation temperature of about 30°C.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3800719&blobtype=pdf
ISSN	15509702
Journal	International Journal of Biomedical Science : IJBS [Int J Biomed Sci]
Volume Number	9
PubMed Central reference number	PMC3800719
Issue Number	3
PubMed reference number	24151453
e-ISSN	15552810
Language	English
Publisher	Master Publishing Group
Publisher Date	2013-09-01
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. © Gamal Enan et al. Licensee Master Publishing Group
Subject Keyword	Lactococcus lactis subsp. lactis Z11 inhibitory activity bacteriocin pathogenic bacteria
Content Type	Text
Resource Type	Article
Subject	Biochemistry, Genetics and Molecular Biology

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