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Characterization and clinical application of mesenchymal stem cells from equine umbilical cord blood.
| Content Provider | Europe PMC |
|---|---|
| Author | Kang, Jun-Gu Park, Sang-Bum Seo, Min-Soo Kim, Hyung-Sik Chae, Joon-Seok Kang, Kyung-Sun |
| Copyright Year | 2013 |
| Abstract | Tendinitis of the superficial digital flexor tendon (SDFT) is a significant cause of lameness in horses; however, recent studies have shown that stem cells could be useful in veterinary regenerative medicine. Therefore, we isolated and characterized equine umbilical cord blood mesenchymal stem cells (eUCB-MSCs) from equine umbilical cord blood obtained from thoroughbred mares during the foaling period. Horses that had tendinitis of the SDFT were treated with eUCB-MSCs to confirm the therapeutic effect. After eUCB-MSCs transplantation, the core lesion in the SDFT was found to decrease. These results suggest that transplantation using eUCB-MSCs could be another source of cell treatment. |
| ISSN | 1229845X |
| Journal | Journal of Veterinary Science |
| Volume Number | 14 |
| PubMed Central reference number | PMC3788164 |
| Issue Number | 3 |
| PubMed reference number | 23820166 |
| e-ISSN | 1976555X |
| DOI | 10.4142/jvs.2013.14.3.367 |
| Language | English |
| Publisher | The Korean Society of Veterinary Science |
| Publisher Date | 2013-06-28 |
| Access Restriction | Open |
| Rights License | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. © 2013 The Korean Society of Veterinary Science. |
| Subject Keyword | cell transplantation equine mesenchymal stem cells umbilical cord blood |
| Content Type | Text |
| Resource Type | Article |
| Subject | Veterinary |