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Where are We Now with Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Infarction?
| Content Provider | Europe PMC |
|---|---|
| Author | Park, Jaechan Hwang, Jeong-Hyun |
| Copyright Year | 2013 |
| Abstract | In spite of the best medical treatment, large hemispheric infarction, resulting from acute occlusion of either the internal carotid or the proximal middle cerebral artery with insufficient collateral blood flow is associated with a high case fatality rate of approximately 60%. Thus, a decompressive hemicraniectomy is considered a life-saving procedure for this devastating disease. Findings of three recent randomized, controlled clinical trials and their meta-analysis showed that early surgical decompression not only reduced the number of case fatalities but also increased the incidence of favorable outcomes. The authors review the pathophysiology, historical background in previous studies, operative timing, surgical technique and clinical outcomes of surgical decompression for malignant hemispheric infarction. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3704996&blobtype=pdf |
| ISSN | 22348565 |
| Journal | Journal of Cerebrovascular and Endovascular Neurosurgery [J Cerebrovasc Endovasc Neurosurg] |
| Volume Number | 15 |
| DOI | 10.7461/jcen.2013.15.2.61 |
| PubMed Central reference number | PMC3704996 |
| Issue Number | 2 |
| PubMed reference number | 23844349 |
| e-ISSN | 22873139 |
| Language | English |
| Publisher | Korean Society of Cerebrovascular Surgeons; Korean Society of Endovascular Surgery |
| Publisher Date | 2013-06-01 |
| Access Restriction | Open |
| Rights License | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. © 2013 Journal of Cerebrovascular and Endovascular Neurosurgery |
| Subject Keyword | Brain edema Cerebral infarction Decompressive surgery Middle cerebral artery |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology (clinical) Surgery Cardiology and Cardiovascular Medicine |
