NDLI: Sunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer.

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Sunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer.

Content Provider	Europe PMC
Author	MUTLU, HASAN BÜYÜKÇELIK, ABDULLAH KAYA, ESER KIBAR, MUSTAFA SEYREK, ERTUĞRUL YAVUZ, SINAN ÇALIKUŞU, ZÜLEYHA
Copyright Year	2013
Abstract	Currently, positron emission tomography with computerized tomography (PET-CT) is the most sensitive technique for detecting extracranial metastases in non-small cell lung cancer (NSCLC). It has been reported that there is a correlation between the maximal standardized uptake value (SUVmax) of primary tumors and prognosis in patients with NSCLC. The effect of sunlight exposure on PET-CT SUVmax value is not known. Therefore, we aimed to evaluate the effect of sunlight exposure on PET-CT SUVmax value in patients with NSCLC. A total of 290 patients with NSCLC from two different regions of Turkey (Kayseri, n=168 and Adana, n=122) that have different climate and sunlight exposure intensity, were included in the study. Age, gender, histology of cancer, cancer stage, smoking status, comorbidity and SUVmax of the primary tumor area at the time of staging were evaluated as prognostic factors. In the multivariate analysis, we detected that the region was the only independent factor affecting SUVmax (P=0.019). We identified that warmer climate and more sunlight exposure significantly increases the SUVmax value of the primary tumor area in patients with NSCLC. Further studies are warranted to clarify the issue.
ISSN	17921074
Journal	Oncology Letters
Volume Number	5
PubMed Central reference number	PMC3576219
Issue Number	3
PubMed reference number	23426076
e-ISSN	17921082
DOI	10.3892/ol.2013.1112
Language	English
Publisher	D.A. Spandidos
Publisher Date	2013-01-07
Access Restriction	Open
Rights License	This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. Copyright © 2013, Spandidos Publications
Subject Keyword	lung cancer maximal standardized uptake value season positron emission tomography
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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