HIV incidence among men who have sex with men in Beijing: a prospective cohort study.

Content Provider	Europe PMC
Author	Li, Dongliang Li, Shuming Liu, Yingjie Gao, Yanjie Yu, Mingrun Yang, Xueying Li, Qingchun Jiang, Shulin Zhou, Zhenhai Zhang, Zheng Yan, Li Jiang, Guiyan Xiao, Dong Pan, Stephen W Luo, Fengji Ruan, Yuhua Shao, Yiming
Copyright Year	2012
Abstract	Objectives(1) To assess the HIV incidence rate among men who have sex with men (MSM) in a large cohort study in Beijing, China and (2) to identify sociodemographic and behavioural risk factors of HIV seroconversion among MSM in Beijing, China.DesignA prospective cohort study.SettingBaseline and follow-up visits were conducted among MSM in Beijing, China.ParticipantsA cohort of 797 HIV-seronegative MSM was recruited from August to December 2009, with follow-up occurring after 6 and 12 months.Primary and secondary outcome measuresAt baseline and follow-up visits, participants reported sociodemographic and sexual behaviour information, and were tested for HIV, herpes simplex virus-2 (HSV-2) and syphilis with whole blood specimens. Cox regression analysis was used to identify factors associated with HIV seroconversion.ResultsMost study participants (86.8%) were retained by the 12-month follow-up. The HIV, HSV-2 and syphilis incidence rates were 8.09 (95% CI 6.92 to 9.26), 5.92 (95% CI 5.44 to 6.40) and 8.06 (95% CI 7.56 to 8.56) cases per 100 person-years, respectively. HIV seroconversion was significantly associated with being <25 years old, having <12 years of education, having >1 male sex partner in the past 6 months, and being syphilis positive or HSV-2 positive.ConclusionsThe HIV incidence among MSM in Beijing is serious. Interventions and treatment of sexually transmitted diseases (STD) should be combined with HIV control and prevention measures among MSM.
Journal	BMJ Open
Volume Number	2
PubMed Central reference number	PMC3533041
Issue Number	6
PubMed reference number	23166133
e-ISSN	20446055
DOI	10.1136/bmjopen-2012-001829
Language	English
Publisher	BMJ Publishing Group
Publisher Date	2012-11-19
Publisher Place	London
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions
Subject Keyword	Epidemiology
Content Type	Text
Resource Type	Article
Subject	Medicine