Association between portal vein color Doppler findings and the severity of disease in cirrhotic patients with portal hypertension.

Content Provider	Europe PMC
Author	Mittal, Puneet Gupta, Ranjana Mittal, Gaurav Kalia, Vishal
Copyright Year	2011
Abstract	BackgroundDoppler ultrasound is the accepted gold standard for assessing direction of flow in the portal vein (PV). Moreover, it is non-invasive; therefore, it is well accepted by the patients and does not interfere with flow hemodynamics.ObjectivesThe present study was aimed to evaluate the association between color Doppler findings and the severity of portal hypertension in patients with cirrhosis.Patients and MethodsThe study group included 50 patients referred for ultrasound (US) evaluation over a period of six months from March to August, 2007. The patients were divided into three groups (Child’ A, B and C) based on Child Pugh classification. The direction of flow in the main portal vein (hepatopetal or nonhepatopetal) and peak venous velocity (PVV) in the main portal vein were measured and correlated with the presence or absence of ascites, splenomegaly, splenic and esophageal varices (assessed by Doppler US). These findings were correlated with clinical features and laboratory findings (using Child Pugh’s criteria).ResultsThere was significant association between the decrease of peak portal venous velocity (PVV) and the increase in Child Pugh score. Hepatofugal flow was seen only in patients with more advanced disease. There was also significant association between PVV and splenic varices and ascites, while PVV was not affected by the presence or absence of esophageal varices or splenomegaly. Presence of a recanalized umbilical vein (UV) was associated with increased PVV even in advanced disease.ConclusionsColor Doppler is an excellent modality for detecting and characterizing the complex hemodynamics of portal hypertension in cirrhosis and they correlate with the clinical stage of disease.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3522358&blobtype=pdf
ISSN	17351065
Journal	Iranian Journal of Radiology [Iran J Radiol]
Volume Number	8
DOI	10.5812/iranjradiol.4489
PubMed Central reference number	PMC3522358
Issue Number	4
PubMed reference number	23329943
e-ISSN	20082711
Language	English
Publisher	Kowsar
Publisher Date	2011-12-25
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2011, Tehran University of Medical Sciences and Iranian Society of Radiology
Subject Keyword	Child Liver Cirrhosis Hypertension, Portal
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging