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Clinical outcomes after combined Ahmed glaucoma valve implantation and penetrating keratoplasty or pars plana vitrectomy.
| Content Provider | Europe PMC |
|---|---|
| Author | Lee, Jin Young Sung, Kyung Rim Tchah, Hung Won Yoon, Young Hee Kim, June Gone Kim, Myoung Joon Kim, Jae Yong Yun, Sung-Cheol Lee, Joo Yong |
| Copyright Year | 2012 |
| Abstract | PurposeTo evaluate whether a combination of penetrating keratoplasty (PKP) or pars plana vitrectomy (PPV) and Ahmed glaucoma valve (AGV) implantation affords a level of success similar to that of AGV implantation alone.MethodsEighteen eyes underwent simultaneous PPV and AGV, 14 eyes with PKP and AGV and 30 eyes with AGV implantation alone were evaluated. Success was defined as attainment of an intraocular pressure (IOP) >5 and <22 mmHg, with or without use of anti-glaucoma medication. Kaplan-Meier survival analysis was performed to compare cumulative survival between the combined surgery groups and the AGV implantation-alone group. Cox proportional hazard regression analysis was conducted to identify factors predictive of success in each of the three groups.ResultsMean (±standard deviation) preoperative IOP was 30.2 ± 10.2 mmHg in the PKP + AGV, 35.2 ± 9.8 mmHg in the PPV + AGV, and 36.2 ± 10.1 mmHg in the AGV implantation-alone group. The cumulative success rate at 18 months was 66.9%, 73.2%, and 70.8% in the three groups, respectively. Neither combined surgery group differed significantly in terms of cumulative success rate compared with the AGV implantation-alone group (p = 0.556, p = 0.487, respectively). The mean number of preoperative anti-glaucoma medications prescribed was significantly associated with success in the PKP + AGV implantation group (hazard ratio, 2.942; p = 0.024).ConclusionsEither PKP or PPV performed in conjunction with AGV implantation afforded similar success rates compared to patients treated with AGV implantation alone. Therefore, in patients with refractory glaucoma who have underlying corneal or retinal pathology requiring treatment with PKP or PPV, AGV implantation can be performed simultaneously. |
| ISSN | 10118942 |
| Journal | Korean Journal of Ophthalmology : KJO |
| Volume Number | 26 |
| PubMed Central reference number | PMC3506817 |
| Issue Number | 6 |
| PubMed reference number | 23204798 |
| e-ISSN | 20929382 |
| DOI | 10.3341/kjo.2012.26.6.432 |
| Language | English |
| Publisher | The Korean Ophthalmological Society |
| Publisher Date | 2012-11-12 |
| Access Restriction | Open |
| Rights License | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. © 2012 The Korean Ophthalmological Society |
| Subject Keyword | Ahmed valve Glaucoma Intraocular pressure Pars plana vitrectomy Penetrating keratoplasty |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |