Nanostructured materials with biomimetic recognition abilities for chemical sensing.

Content Provider	Europe PMC
Author	Bajwa, Sadia Zafar Mustafa, Ghulam Samardzic, Renata Wangchareansak, Thipvaree Lieberzeit, Peter A
Copyright Year	2012
Abstract	Binding features found in biological systems can be implemented into man-made materials to design nanostructured artificial receptor matrices which are suitable, e.g., for chemical sensing applications. A range of different non-covalent interactions can be utilized based on the chemical properties of the respective analyte. One example is the formation of coordinative bonds between a polymerizable ligand (e.g., N-vinyl-2-pyrrolidone) and a metal ion (e.g., Cu(II)). Optimized molecularly imprinted sensor layers lead to selectivity factors of at least 2 compared to other bivalent ions. In the same way, H-bonds can be utilized for such sensing purposes, as shown in the case of Escherichia coli. The respective molecularly imprinted polymer leads to the selectivity factor of more than 5 between the W and B strains, respectively. Furthermore, nanoparticles with optimized Pearson hardness allow for designing sensors to detect organic thiols in air. The ‘harder’ MoS2 yields only about 40% of the signals towards octane thiol as compared to the ‘softer’ Cu2S. However, both materials strongly prefer molecules with -SH functionality over others, such as hydrocarbon chains. Finally, selectivity studies with wheat germ agglutinin (WGA) reveal that artificial receptors yield selectivities between WGA and bovine serum albumin that are only about a factor of 2 which is smaller than natural ligands.
ISSN	19317573
Journal	Nanoscale Research Letters
Volume Number	7
PubMed Central reference number	PMC3434081
Issue Number	1
PubMed reference number	22721566
e-ISSN	1556276X
DOI	10.1186/1556-276x-7-328
Language	English
Publisher	Springer
Publisher Date	2012-06-21
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright ©2012 Bajwa et al.; licensee Springer.
Subject Keyword	Bivalent copper ions Organic vapors Wheat germ agglutinin lectin Escherichia coli Quartz crystal microbalance
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Condensed Matter Physics Materials Science