Identification of patients at risk for hereditary colorectal cancer.

Content Provider	Europe PMC
Author	Mishra, Nitin Hall, Jason
Abstract	Diagnosis of hereditary colorectal cancer syndromes requires clinical suspicion and knowledge of such syndromes. Lynch syndrome is the most common cause of hereditary colorectal cancer. Other less common causes include familial adenomatous polyposis (FAP), Peutz-Jeghers syndrome (PJS), juvenile polyposis syndrome, and others. There have been a growing number of clinical and molecular tools used to screen and test at risk individuals. Screening tools include diagnostic clinical criteria, family history, genetic prediction models, and tumor testing. Patients who are high risk based on screening should be referred for genetic testing.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3423884&blobtype=pdf
ISSN	15310043
Volume Number	25
DOI	10.1055/s-0032-1313777
PubMed Central reference number	PMC3423884
Issue Number	2
PubMed reference number	23730221
Journal	Clinics in Colon and Rectal Surgery [Clin Colon Rectal Surg]
e-ISSN	15309681
Language	English
Publisher	Thieme Medical Publishers
Publisher Date	2012-06-01
Publisher Place	333 Seventh Avenue, New York, NY 10001, USA.
Access Restriction	Open
Rights License	© Thieme Medical Publishers
Subject Keyword	Lynch syndrome familial adenomatous polyposis Peutz-Jeghers syndrome
Content Type	Text
Resource Type	Article
Subject	Gastroenterology Surgery